Description: Multiple Testing Procedures and Applications to Genomics, Hardcover by Dudoit, Sandrine; Van Der Laan, Mark J., ISBN 0387493166, ISBN-13 9780387493169, Brand New, Free P&P in the UK
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.
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Book Title: Multiple Testing Procedures and Applications to Genomics
Publisher: Springer-Verlag New York Inc.
Publication Year: 2007
Subject: Engineering & Technology, Biology, Mathematics, Healthcare System
Number of Pages: 590 Pages
Language: English
Publication Name: Multiple Testing Procedures with Applications to Genomics
Item Weight: 1100 g
Type: Textbook
Author: Sandrine Dudoit, Mark J. Van Der Laan
Series: Springer Series in Statistics
Format: Hardcover