Mechanisms of Morphogenesis by Jamie A. Davies Paperback Book

Description: FREE SHIPPING UK WIDE Mechanisms of Morphogenesis by Jamie A. Davies Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. Across foundational, applied and methods-based chapters, this book examines molecular nano-machines cooperation, generate cell shape, direct cell migration, and shape, form and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications.Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues. FORMAT Paperback CONDITION Brand New Author Biography Since 1995 Davies has run his own laboratory at the University of Edinburgh, with a multidisciplinary focus on discovering how mammalian organs construct themselves and how we can use apply knowledge to build new tissues and organs for those in need. Some of the work of his 20-strong research team is conventional developmental biology; identifying signals and mechanisms used in natural organ development. Some is bioinformatic analysis (we host the editorial office of an international database for renal development – – funded by the USA National Institutes of Health, and the database, an international effort for the International Union of Basic and Clinical Pharmacology). Some of his work is in tissue engineering – his lab has recently developed a method to produce engineered fetal kidneys from simple suspensions of stem cells, an activity that attracted considerable press attention last year. Finally, his lab is pioneering the application of synthetic biology techniques to tissue engineering, to program cells to make structures that are designed rather than evolved.Davies has published around 140 research papers in the field of mammalian development, has published one major specialist monograph (Mechanisms of Morphogenesis, Elsevier, 2005 2nd Ed 2014), one public engagement book (Life Unfoloding, OUP, 2013 (Hardback), 2015 (paperback), now in translation also) and has edited three multi-author books in the fields of development, stem cells and tissue engineering. His contributions to research and teaching in this area have been recognized by having been elected a Fellow of the Royal Society of Biology, a Fellow of the Royal Society of Medicine and a Principal Fellow of the Higher Education Academy. Davies served as Deputy Chair of the National Centre for 3Rs, a government agency that promotes research that refines, reduces or replaces animal experiments. He has also served as Editor-in-Chief of the research journal Organogenesis for 8 years, and is currently an Editor of Journal of Anatomy and PLOS One. Table of Contents Section I: Introduction 1. General introduction – the aims and structure of this book. 2. Key principles of morphogenesis 3. The power and limitations of self-assemblySection II: Cell shape and the cell morphogenesis 4. Morphogenesis of individual cells 5. Animal cell shape: the importance of the cytoskeleton 6. Cellular morphogenesis in plantsSection III: Cell Migration 7. Cell migration in development: a brief overview 8. The nanomachinery of locomotion 9. Guidance by chemotaxis 10. Guidance by galvanotaxis 11. Guidance by contact 12. Waypoint navigation in the embryo 13. Cooperative migration of mesenchymal cells 14. Condensation of cellsSection IV: Epithelial Morphogenesis 15. The epithelial state: a brief overview 16. Neighbour exchange and convergent extension 17. Closure of holes 18. Invagination and evagination 19. Epithelial fusion 20. Epithelial branching 21. Boundaries to epithelial movementSection V: Morphogenesis by cell proliferation and death 22. Growth, proliferation and death: a brief overview 23. Morphogenesis by orientated cell division 24. Morphogenesis by elective cell deathSection VI: Morphogenesis in context 25. From mechanisms to morphology: a brief overview 26. Morphogenesis in embryos: some illustrative examples 27. Morphogenesis in organoids, embryoids and engineered tissues 28. Pathological morphogenesisSection VII: Modelling morphogenesis 29. Modelling morphogenesis: a brief overview 30. Mechanical and mathematical models of morphogenesis 31. Modelling using living cells – tissue engineering and synthetic morphologySection VIII: Conclusion and perspectives 32. Conclusion and perspectives Details ISBN0323999654 Publisher Elsevier Science & Technology Year 2023 Edition 3rd ISBN-13 9780323999656 Format Paperback Imprint Academic Press Inc Place of Publication Oxford Country of Publication United Kingdom AU Release Date 2023-08-01 NZ Release Date 2023-08-01 Author Jamie A. Davies ISBN-10 0323999654 Pages 532 Edition Description 3rd edition Replaces 9780123910622 Alternative 9780323985284 DEWEY 571.833 Audience Professional & Vocational Publication Date 2023-06-14 UK Release Date 2023-06-14 We've got this At The Nile, if you're looking for it, we've got it. 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